Guest Blogger James Le Fanu: The Last Days of the Façade of Knowing

The philosopher Thomas Nagel in a memorable phrase laments ‘the ludicrous overuse of evolutionary biology to explain everything about life’ — where there is nothing too sensational, extraordinary or bizarre about the living world that cannot be accounted for as having evolved to be that way over billions of years by the same known materialistic process of natural selection acting on random genetic mutation. This façade of knowing cannot last, of course, and 20 years or so hence historians and commentators will rightly wonder how science could conceivably have endorsed so simplistic a theory to explain the billion fold complexities of the living world — and for so long. The impetus for that disillusionment can only come from within science Read More ›

Ayala: “For the record, I read Signature in the Cell”

Over at BioLogos, Professor Francisco Ayala has responded to Signature of Controversy — the collection of responses to criticisms of Signature in the Cell. As with the previous Ayala response at BioLogos, this one includes an introduction by Darrell Falk. The burden of Ayala’s response is to wax indignant that some of us have suggested, based on his original “response” to Signature in the Cell, that he had not actually read the book. Why would we suggest that? Well, because he so profoundly misrepresented Meyer’s thesis. Here’s what he said: “The keystone argument of Signature [sic] of the Cell is that chance, by itself, cannot account for the genetic information found in the genomes of organisms.” He goes on to Read More ›

Let’s Do the Math Again

Earlier today I criticized Calvin College biologist Steve Matheson’s incorrect view of “junk” DNA. Matheson had argued in February that the human genome contains about 190,000 introns (stretches of non-protein-coding DNA that interrupt protein-coding genes), of which “only a handful” had important functional roles. “How many? Oh, probably a dozen,” he wrote, “but let’s be really generous. Let’s say that a hundred introns in the human genome are known to have ‘important functional roles.’ Oh fine, let’s make it a thousand.”On the contrary, I pointed out that at least 90% of genes are alternatively spliced, meaning that 0.9 x 190,000 = 171,000 introns are involved in alternative splicing, an essential process that helps to ensure that the proper proteins are Read More ›

Matheson’s Intron Fairy Tale

The failure to recognize the importance of introns “may well go down as one of the biggest mistakes in the history of molecular biology.” –John Mattick, Molecular biologist, University of Queensland, quoted in Scientific American On Friday, May 14, I watched as Steve Meyer faced his critics — two of them anyway, Art Hunt and Steve Matheson — at Biola University in Los Angeles. Matheson had previously claimed that Meyer misrepresented introns in his book, Signature in the Cell. (Introns are non-protein-coding sequences of DNA that occur within protein-coding regions.) In a blog post dated February 14, Matheson had accused Meyer of “some combination of ignorance, sloth, and duplicity” for stating in his book that although introns do not encode Read More ›

Fossil Finds Show Cambrian Explosion Getting More Explosive

Cephalopods, which include marine mollusks like squid, octopus, and cuttlefish, are now being reported in the Cambrian explosion fossils. As a recent BBC news article reports: “We go from very simple pre-Cambrian life-forms to something as complex as a cephalopod in the geological blink of an eye, which illustrates just how quickly evolution can produce complexity,” said [evolutionary biologist Martin] Smith. Keep in mind here that “evolution” is a placeholder term for an as-of-yet uncovered mechanism that produces animals like Cephalopods in a “geological blink of an eye.” Darwin’s Dilemma is not solved by vague appeals “how quickly” evolution can operate. All this follows on the heels of recent fossil findings that push phylum Bryozoa back into the Cambrian period, Read More ›