We are nearing a half-century since Eigen wrote about this paradox, and it “still challenges theoretical biologists.”
In a previous article I described the evidence that cooption faces insurmountable mathematical challenges in explaining the origins of such complex molecular machines as the bacterial flagellum.
Leading lights in origin-of-life research share their work and thoughts in a series of open-access articles about chemical evolution.
In effect, protein engineers are using the power of random change plus intelligent design to see what if anything will improve function.
About the movement of organelles: There are molecular motor proteins that haul them around!