Lang and Rice cite a number of articles to show that loss-of-function mutations are just a small minority of those found in studies of organisms.
Their review pretty much completely misses the mark. Nonetheless, it is a good illustration of how sincere-yet-perplexed professional evolutionary biologists view the data.
Coyne is sure this is going to come as a rude shock, to our colleague and contributor Dr. Behe in particular, “a slap in the face of IDers like Michael Behe — a fish slap like the one below.”
Professor Lenski’s contrasting of the frequency versus importance of evolutionary changes is misconceived and his illustrations are inapt.
In previous articles I have discussed how biological organisms exhibit patterns that are highly analogous to computer programs written by humans.