Tag: loop extrusion
Topoisomerase Origins Defy Darwinian Explanations
A review of the topoisomerase family of molecular machines that repair DNA ignores where they came from. Another article tries but has no answers.
DNA Packing: One of the Supreme Wonders of Nature
The cell packs two meters of DNA into a 10-micron nucleus. How? The machinery is as intelligently designed as the genome itself.
Cells Use Loop Extrusion to Keep DNA Optimized
A paper illustrates the action of DNA loop extrusion processes, which serve multiple functions to maintain the genome, with an interesting graphic: gears.