Professor Lenski’s contrasting of the frequency versus importance of evolutionary changes is misconceived and his illustrations are inapt.
In previous articles I have discussed how biological organisms exhibit patterns that are highly analogous to computer programs written by humans.
Computer methods of analyzing mutations are widely used because they are generally accurate. They do not suddenly lose their accuracy when I cite them.
Out of consideration for readers who want to judge the disagreements for themselves, that seems like the way to go.
A very common way to try to discredit an argument is to exaggerate it, ignore distinctions an author makes, and/or change carefully qualified claims into bizarre absolutes.