It’s worth engaging him, since Swamidass is the relatively rare critic of ID who works at tackling arguments for design in a substantive fashion.
Dennis Venema sought to persuade his fellow Christians that genetic science had disproven the traditional idea of a “bottleneck” of two human ancestors.
Darwin himself realized that any kind of significant saltational change would imply a miracle-like intelligent intervention.
Some have claimed that for humans the coalescence to one (or first coalescent) does not happen for well over a million years back in time, calling into question the idea of a single-couple human origin.
To maintain at this point that “All Is Well” with evolution you have to be in a state of serious denial.