We are nearing a half-century since Eigen wrote about this paradox, and it “still challenges theoretical biologists.”
Coyne is sure this is going to come as a rude shock, to our colleague and contributor Dr. Behe in particular, “a slap in the face of IDers like Michael Behe — a fish slap like the one below.”
Explaining this sort of phenomenon by slight, successive modification, as Darwin envisaged, seems problematic.
French philosopher René Descartes conceived of living things as complex machines, a concept now known as the “machine metaphor.”
All of this calls to mind a comment from biologist John Mattick, a critic of the junk DNA paradigm.