Tag: spindle assembly checkpoint
Engineered Elegance: Checkpoint Pathways of the Cell Cycle
One of the most incredible features of cellular life is the capability of self-replication.
Engineered Elegance: Generating the Wait Anaphase Signal
Even a single unattached kinetochore is sufficient to trigger the wait anaphase signal, which inhibits activation of the APC/C that drives entry into anaphase.
The Elegant Spindle Assembly Checkpoint
Without this exquisitely engineered system, the cell risks distributing an uneven number of chromosomes to the daughter cells.