Only a freely acting, designing agent resolves the mystery. Only such an agent creates, truly, ex nihilo.
A memory of past events helps a cell learn how to respond to recurring threats and protect the genome.
Considering Hamlet, the Aristotelian can appreciate both the physiology and the drama to which the mechanist is blind.
One might add that this analysis applies to the world of life as a whole.
A peculiar habit of disassociation is widespread among many who study the brain.