That Darwinism seems even superficially plausible depends completely on the ability of living things to reproduce themselves without significant degradation.
You do not need to study mutations for thirty years to predict that bombarding plant chromosomes with radiation will not lead to major agricultural advances.
Natural selection is not, after all, the one natural process in the universe that can make nature run backward.
Quite honestly, I think we should be grateful to people like Coyne and Hawking, who carry materialism to its logical conclusions.
Reproduction is the most fundamental characteristic of life. We see it happen everywhere, so we may feel there is nothing “unnatural” about it.