“How many other scientific disciplines have utterly failed to explain the salient phenomenon of the system they study?” I can think of one.
The pretense not to know things is at the root of Darwinist/atheist/materialist ideology.
The firm belief in extraterrestrial life — a belief nearly universal in the scientific community — is an act of faith.
Oddities of neuroscience that indicate that there is more going on in the brain than mere chemistry.
Douglas Hofstadter argued in much the same vein as Henry Markham, that the brain can be understand in rules-bound machine terms.