The only realistic resolution favorable to materialism would be offered by the hope, still elusive, of a signal from space.
Could exoplanets support life that has a different chemical composition? Absent details about the composition, who knows?
Why do they keep funding it? Same reason we fund evolutionary biology.
Please understand that this is the best they’ve got.
A far more effective materialist response to fine-tuning is the “Copernican” Principle (though Copernicus would have rejected it), sometimes called the Principle of Mediocrity.