C. S. Lewis was an agnostic before he became a Christian, so he understood the spell of unbelief.
If mutations are the raw material for evolution, they are like explosives with unpredictable effects.
Fierce debates have occurred among intelligent design theorists — mostly behind the scenes — about the causal role of DNA.
Evolution is an implication — that is, an empirical consequence — of design.
What if there is genuine directionality in mutation? An important paper addresses the subject.