Powerful Protein-Folding Algorithm AlphaFold Foiled by Singletons
We now know that biological information involves far more than just an organism’s proteome.
Proteome Is Analogous to Language
A paper likens the proteome to a language with a “quasi-universal grammar” possessing the minimum complexity necessary to function as a cell.
Ribosomes Optimized for Speed, Flexibility
The DNA translation machines in the cell show unexpected complexity, forcing molecular biologists to revise what they thought they knew about ribosomes.
Subcellular Map of the Human Proteome Reveals “Highly Complex Architecture”
The degree of regulation and control required for this system is not only enormous, but contrary to evolutionary expectations.