Brian Miller discusses the Levinthal paradox of the interactome, the long odds of blind processes assembling the first cell, and the challenge of cell death.
Brian Miller and Eric Anderson discuss Jeremy England’s origin-of-life ideas and the RNA World hypothesis.
Physicist Eric Hedin talks about the challenge the second law of thermodynamics poses for naturalistic scenarios for the origin of the first living organism.
No one — not even the most elite of origin-of-life scientists — has a clue how life could have arisen through blind natural forces on the early Earth.
Such an event would have involved a breathtaking increase in new information, and physics tells us clearly that mindless nature only degrades information.