Lang and Rice cite a number of articles to show that loss-of-function mutations are just a small minority of those found in studies of organisms.
A paper likens the proteome to a language with a “quasi-universal grammar” possessing the minimum complexity necessary to function as a cell.
It is a difficult question because, setting aside many other problems, the very starting point — the protein-coding gene — is highly complex.
Leading lights in origin-of-life research share their work and thoughts in a series of open-access articles about chemical evolution.
Philosophical questions like who we are and where we came from are surely worth considering. But nothing in these documents will bring students closer to being able to do so in an informed manner.