A reader must ask if an RNA molecule could possibly govern chemical reactions, suppress free-riders, support co-operators, and act in its own self-interest.
Professor Hansma maintains that sets of integrated reactions could have been directed by natural selection to gradually evolve into an autonomous cell.
Hossenfelder’s strongest argument is that many fine-tuning parameters cannot in fact be quantified.
My interlocutor was Helen Hansma who pioneered the mica-sheet origin-of-life model.
I particularly appreciate how his arguments complement my own analyses addressing the origin of life.